1. Start Gently: Retinol Microdose 0.25%
Perfect for beginners. Add 1–2 drops every evening into your moisturizer or serum.
Helps the skin adapt slowly, reducing the risk of irritation.
Must be used together with a cream or serum.
2. For Advanced Users: Retinol Routine Booster 1%
Ideal for those already familiar with retinol.
How to introduce: Weeks 1-2: once a week. After week 2: increase to twice a week (maximum)
Also requires pairing with a moisturizer.
3. All-In-One Option: Collagen Reactivate PM Lifting Treatment Moisturizer + Retinol
A nighttime cream that already contains retinol, designed for lifting, firming, and smoother texture.
Benefits:
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Improves firmness and skin density
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Reduces fine lines
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Enhances comfort during retinol use
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Provides a complete evening routine — no additional moisturizer needed
Perfect for:
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Those who want simplicity
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Sensitive or reactive skin types
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Anyone wanting a comfortable yet effective retinol experience
How to Choose Between the Three Options
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Microdose 0.25% & Booster 1%: use with another moisturizer — they are boosters, not standalone creams.
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Collagen Reactivate PM: an all-in-one retinol night cream.
Research Sources:
Kang S. et al., JAAD, 1995.
Retinoids increase cell turnover → early dryness & irritation, especially when introduced too fast.
Kligman D. & Kligman A.M., JAAD, 1986.
Moisturizers reduce irritation by improving barrier function during initial retinoid use.
Mukherjee S. et al., Clinical Interventions in Aging, 2006.
Lower-dose retinoids offer similar long-term benefits with fewer side effects.
Kafi R. et al., Archives of Dermatology, 2007.
12-week clinical study shows increased collagen I & III, improved firmness, and reduced wrinkles.
Varani J. et al., Journal of Investigative Dermatology, 2000.
Demonstrates reduced collagen breakdown and thicker dermis.
Kang S. et al., Dermatologic Surgery, 2001.
Measured improvements in firmness, texture, and wrinkle depth after 24 weeks.
Papakonstantinou E. et al., Biomolecules, 2023.
Summarizes evidence for retinol increasing firmness, density, and skin elasticity.